Upregulation of the Nr2f1-A830082K12Rik gene pair in murine neural crest cells results in a complex phenotype reminiscent of Waardenburg syndrome type 4

Waardenburg syndrome is a neurocristopathy characterized by a combination of skin and hair depigmentation, and inner ear defects. In the type 4 form, these defects show comorbidity with Hirschsprung disease, a disorder marked by an absence of neural ganglia in the distal colon, triggering functional...

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Principais autores:	Karl-F. Bergeron, Chloé M. A. Nguyen, Tatiana Cardinal, Baptiste Charrier, David W. Silversides, Nicolas Pilon
Format:	Artigo
Jezik:	Inglês
Izdano:	The Company of Biologists 2016-11-01
Serija:	Disease Models & Mechanisms
Teme:	Enteric nervous system Hirschsprung disease Melanocytes Mouse model Neural crest cells Waardenburg syndrome
Online dostop:	http://dmm.biologists.org/content/9/11/1283
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