Role of Estrogen Receptors α and β in a Murine Model of Asthma: Exacerbated Airway Hyperresponsiveness and Remodeling in ERβ Knockout Mice

Epidemiological data suggests increased prevalence of asthma in females than males, suggesting a plausible role for sex-steroids, especially estrogen in the lungs. Estrogen primarily acts through estrogen-receptors (ERα and ERβ), which play a differential role in asthma. Our previous studies demonst...

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Auteurs principaux:	Rama Satyanarayana Raju Kalidhindi, Nilesh Sudhakar Ambhore, Sangeeta Bhallamudi, Jagadish Loganathan, Venkatachalem Sathish
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2020-02-01
Collection:	Frontiers in Pharmacology
Sujets:	estrogen receptor alpha sex difference mixed allergen flexiVent fibronectin collagen
Accès en ligne:	https://www.frontiersin.org/article/10.3389/fphar.2019.01499/full
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