Deep sequence analysis of HIV adaptation following vertical transmission reveals the impact of immune pressure on the evolution of HIV.

Human immunodeficiency virus (HIV) can adapt to an individual's T cell immune response via genomic mutations that affect antigen recognition and impact disease outcome. These viral adaptations are specific to the host's human leucocyte antigen (HLA) alleles, as these molecules determine which peptid...

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Hlavní autoři:	Jennifer Currenti, Abha Chopra, Mina John, Shay Leary, Elizabeth McKinnon, Eric Alves, Mark Pilkinton, Rita Smith, Louise Barnett, Wyatt J McDonnell, Michaela Lucas, Francine Noel, Simon Mallal, Joseph A Conrad, Spyros A Kalams, Silvana Gaudieri
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2019-12-01
Edice:	PLoS Pathogens
On-line přístup:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1008177&type=printable
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