Tropomyosin receptor kinase B (TrkB) signalling: targeted therapy in neurogenic tumours

Abstract Tropomyosin receptor kinase B (TrkB), a transmembrane receptor protein, has been found to play a pivotal role in neural development. This protein is encoded by the neurotrophic receptor tyrosine kinase 2 (NTRK2) gene, and its abnormal activation caused by NTRK2 overexpression or fusion can...

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Detalhes bibliográficos

Principais autores:	Yuehua Li, Chengjiang Wei, Wei Wang, Qingfeng Li, Zhi‐Chao Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2023-03-01
Colecção:	The Journal of Pathology: Clinical Research
Assuntos:	TrkB tyrosine kinase NTRK abnormal activation gene fusion neurogenic tumours
Acesso em linha:	https://doi.org/10.1002/cjp2.307
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