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ChREBP binding to fatty acid synthase and L-type pyruvate kinase genes is stimulated by glucose in pancreatic β-cells

Pancreatic β-cell dysfunction is central to the pathogenesis of type 2 diabetes and may involve secretory failure through glucolipotoxity. The relative importance of the transcription factors carbohydrate-responsive element binding protein (ChREBP), sterol-responsive element binding protein-1c (SREB...

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Detaylı Bibliyografya
Asıl Yazarlar: Gabriela da Silva Xavier, Guy A. Rutter, Frédérique Diraison, Chrysovalantis Andreolas, Isabelle Leclerc
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2006-11-01
Seri Bilgileri:Journal of Lipid Research
Konular:
Online Erişim:http://www.sciencedirect.com/science/article/pii/S002222752043384X
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