BACE1 Deficiency Causes Abnormal Neuronal Clustering in the Dentate Gyrus
BACE1 is validated as Alzheimer's β-secretase and a therapeutic target for Alzheimer's disease. In examining BACE1-null mice, we discovered that BACE1 deficiency develops abnormal clusters of immature neurons, forming doublecortin-positive neuroblasts, in the developing dentate gyrus, mainly in the...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Elsevier
2017-07-01
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| Edice: | Stem Cell Reports |
| Témata: | |
| On-line přístup: | http://www.sciencedirect.com/science/article/pii/S2213671117302370 |
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