Inflammatory signaling on cytochrome P450-mediated drug metabolism in hepatocytes

Cytochrome P450 (CYP450) enzymes are membrane-bound blood proteins that are vital to drug detoxification, cell metabolism, and homeostasis. CYP450s belonging to CYP families 1–3 are responsible for nearly 80% of oxidative metabolism and complete elimination of approximately 50% of all common clinica...

תיאור מלא

מידע ביבליוגרפי

Principais autores:	Xiaokang Wang, Jiaoyu Rao, Zhiyi Tan, Tianrong Xun, Jingqian Zhao, Xixiao Yang
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2022-10-01
סדרה:	Frontiers in Pharmacology
נושאים:	cytochrome P450 inflammatory signaling drug metabolism hepatocytes clinical application
גישה מקוונת:	https://www.frontiersin.org/articles/10.3389/fphar.2022.1043836/full
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