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BioPETsurv: Methodology and open source software to evaluate biomarkers for prognostic enrichment of time-to-event clinical trials.

Biomarkers can be used to enrich a clinical trial for patients at higher risk for an outcome, a strategy termed "prognostic enrichment." Methodology is needed to evaluate biomarkers for prognostic enrichment of trials with time-to-event endpoints such as survival. Key considerations when considering...

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Detalhes bibliográficos
Principais autores: Si Cheng, Kathleen F Kerr, Heather Thiessen-Philbrook, Steven G Coca, Chirag R Parikh
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2020-01-01
coleção:PLoS ONE
Acesso em linha:https://doi.org/10.1371/journal.pone.0239486
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