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NeoAdjuvant pembrolizumab and STEreotactic radiotherapy prior to nephrectomy for renal cell carcinoma (NAPSTER): A phase II randomised clinical trial

Background: Surgery remains the standard of care for localised renal cell carcinoma (RCC). Nevertheless, nearly 50% of patients with high-risk disease experience relapse after surgery, with distant sites being common. Considering improved outcomes in terms of disease-free survival with adjuvant immu...

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Principais autores: Muhammad Ali, Simon Wood, David Pryor, Daniel Moon, Mathias Bressel, Arun A. Azad, Catherine Mitchell, Declan Murphy, Homi Zargar, Nick Hardcastle, Jamie Kearsley, Renu Eapen, Lih Ming Wong, Katharine Cuff, Nathan Lawrentschuk, Paul J. Neeson, Shankar Siva
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2023-06-01
Series:Contemporary Clinical Trials Communications
Assuntos:
Neoadjuvant
Pembrolizumab
Stereotactic radiotherapy
Renal cell carcinoma
Nephrectomy
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2451865423000911
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