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Venetoclax-Ibrutinib Combinations as First-Line Therapy in Chronic Lymphocytic Leukemia: A Meta-Analysis of Randomized Controlled Trials with GRADE Approach

Objective: Chronic lymphocytic leukemia (CLL) treatment has shifted from chemoimmunotherapy to targeted agents. Venetoclax and ibrutinib, which act through complementary mechanisms, have shown promise in achieving deep remissions. Their combination may enhance efficacy, but pooled evidence from rand...

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Główni autorzy: Lokman Hekim Tanrıverdi, Ahmet Sarıcı
Format: Artigo
Język:Inglês
Wydane: Erzincan Binali Yıldırım University School of Medicine 2026-01-01
Seria:Archives of Basic and Clinical Research
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Dostęp online:https://abcresearch.net/articles/venetoclax-ibrutinib-combinations-as-first-line-therapy-in-chronic-lymphocytic-leukemia-a-meta-analysis-of-randomized-controlled-trials-with-grade-approach/doi/ABCR.2025.25386
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