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Automated single-cell proteomics providing sufficient proteome depth to study complex biology beyond cell type classifications

Abstract The recent technological and computational advances in mass spectrometry-based single-cell proteomics have pushed the boundaries of sensitivity and throughput. However, reproducible quantification of thousands of proteins within a single cell remains challenging. To address some of those li...

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Principais autores: Claudia Ctortecka, Natalie M. Clark, Brian W. Boyle, Anjali Seth, D. R. Mani, Namrata D. Udeshi, Steven A. Carr
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2024-07-01
Series:Nature Communications
Acceso en liña:https://doi.org/10.1038/s41467-024-49651-w
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