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Peptide-derivatized SB105-A10 dendrimer inhibits the infectivity of R5 and X4 HIV-1 strains in primary PBMCs and cervicovaginal histocultures.

Peptide dendrimers are a class of molecules that exhibit a large array of biological effects including antiviral activity. In this report, we analyzed the antiviral activity of the peptide-derivatized SB105-A10 dendrimer, which is a tetra-branched dendrimer synthetized on a lysine core, in activated...

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Autori principali: Isabella Bon, David Lembo, Marco Rusnati, Alberto Clò, Silvia Morini, Anna Miserocchi, Antonella Bugatti, Sonia Grigolon, Giuseppina Musumeci, Santo Landolfo, Maria Carla Re, Davide Gibellini
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2013-01-01
Serie:PLoS ONE
Accesso online:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24116111/?tool=EBI
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