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Evaluation of early chemotherapy response by combining static- and dynamic [18F]FDG-PET with diffusion-weighted MRI in subcutaneous patient-derived endometrial cancer mouse models

Abstract Background The combination of carboplatin and paclitaxel is the standard chemotherapy for treatment of high-risk and recurrent endometrial cancer. Evaluation of treatment response by diagnostic imaging is routinely carried out months after start of treatment, and is based on changes in tumo...

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Principais autores: Heidi Espedal, Jenny M. Lyngstad, Hege F. Berg, Marta E. Hjelmeland, Kristine E. Fasmer, Camilla Krakstad, Ingfrid S. Haldorsen
Format: Artigo
Sprog:Inglês
Udgivet: SpringerOpen 2025-04-01
Serier:EJNMMI Research
Fag:
Preclinical imaging
Treatment response
Dynamic PET
Endometrial cancer
Organoid models
Chemotherapy
Online adgang:https://doi.org/10.1186/s13550-025-01235-5
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