Butyrate modifies epigenetic and immune pathways in peripheral mononuclear cells from children with neurodevelopmental disorders associated with chromatin dysregulation

Pathogenic DNA variants in chromatin-related genes constitute an important minority of neurodevelopmental disorders (NDDs). Epigenetic mechanisms, including chromatin regulation driven by genetic or environmental factors, are increasingly recognised as key contributors to pathogenesis of diverse NDD...

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Detaylı Bibliyografya

Asıl Yazarlar:	Jessica P. Hayes, Velda X. Han, Brooke A. Keating, Hiroya Nishida, Erica Tsang, Xianzhong Lau, Ruwani Dissanayake, Nader Aryamanesh, Wendy Gold, Melanie Wong, Carolyn Ellaway, Brian S. Gloss, Shekeeb S. Mohammad, Markus J. Hofer, Peter Valtchev, Shrujna Patel, Russell C. Dale
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Elsevier 2026-01-01
Seri Bilgileri:	Neurotherapeutics
Konular:	Neurodevelopmental disorders Neuroregression Epigenetics Chromatin Histone deacetylase inhibition Butyrate
Online Erişim:	http://www.sciencedirect.com/science/article/pii/S1878747925002703
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