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Exploring the feasibility of using long-term stored newborn dried blood spots to identify metabolic features for congenital heart disease screening

Abstract Congenital heart disease (CHD) represents a significant contributor to both morbidity and mortality in neonates and children. There’s currently no analogous dried blood spot (DBS) screening for CHD immediately after birth. This study was set to assess the feasibility of using DBS to identif...

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Principais autores: Scott R. Ceresnak, Yaqi Zhang, Xuefeng B. Ling, Kuo Jung Su, Qiming Tang, Bo Jin, James Schilling, C. James Chou, Zhi Han, Brendan J. Floyd, John C. Whitin, Kuo Yuan Hwa, Karl G Sylvester, Henry Chubb, Ruben Y. Luo, Lu Tian, Harvey J. Cohen, Doff B. McElhinney
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-11-01
Serier:Biomarker Research
Fag:
Congenital Heart Disease
Screening and classification
Metabolite profiling
Dried blood spot
LC-MS/MS
Online adgang:https://doi.org/10.1186/s40364-023-00536-y
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