Multi-omics analyses identify gut microbiota-fecal metabolites-brain-cognition pathways in the Alzheimer’s disease continuum

Abstract Background Gut microbiota dysbiosis is linked to Alzheimer’s disease (AD), but our understanding of the molecular and neuropathological bases underlying such association remains fragmentary. Methods Using 16S rDNA amplicon sequencing, untargeted metabolomics, and multi-modal magnetic resona...

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Principais autores:	Han Zhao, Xia Zhou, Yu Song, Wenming Zhao, Zhongwu Sun, Jiajia Zhu, Yongqiang Yu
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2025-02-01
Series:	Alzheimer’s Research & Therapy
Assuntos:	Alzheimer’s disease Gut microbiome Fecal metabolome Neuroimaging Cognition
Acceso en liña:	https://doi.org/10.1186/s13195-025-01683-0
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