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Habbe Gule Aakh prevents glycolytic program and alleviates disease progression in a rheumatoid arthritis animal model

BackgroundThe acquired tumorigenic phenotype of the resident fibroblast like synoviocytes (FLS) is cornerstone to exacerbating rheumatoid arthritis (RA) disease progression. Toll like receptor 4 (TLR4) signalling can sustain the proliferative and invasive phenotype of these synoviocytes resulting in...

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Principais autores: Arulkumaran Rithvik, Shangomitra Bhattacharjee, Manshi Kumari Gupta, C. Sudandiradoss, Abdul Wadud, Mahaboobkhan Rasool
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-08-01
coleção:Frontiers in Immunology
Assuntos:
rheumatoid arthritis
fibroblast-like synoviocytes
Habbe Gule Aakh
toll-like receptor 4
glycolysis
TIMP1
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1633061/full
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