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DARTS: an open-source Python pipeline for Ca2+ microdomain analysis in live cell imaging data

Ca2+ microdomains play a key role in intracellular signaling processes. For instance, they mediate the activation of T cells and, thus, the initial adaptive immune system. They are, however, also of utmost importance for activation of other cells, and a detailed understanding of the dynamics of thes...

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Hoofdauteurs: Lena-Marie Woelk, Dejan Kovacevic, Hümeyra Husseini, Fritz Förster, Fynn Gerlach, Franziska Möckl, Marcus Altfeld, Andreas H. Guse, Björn-Philipp Diercks, René Werner
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2024-01-01
Reeks:Frontiers in Immunology
Onderwerpen:
intracellular signaling
Ca2+ microdomains
live cell imaging
image analysis
shape normalization
Python
Online toegang:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1299435/full
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