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Blood-Brain Barrier Dysfunction Precedes Cognitive Decline and Neurodegeneration in Diabetic Insulin Resistant Mouse Model: An Implication for Causal Link

Diabetic insulin resistance and pro-diabetic diet are reported to increase dementia risk through unknown mechanisms. Emerging evidence suggests that the integrity of blood-brain barrier (BBB) is central to the onset and progression of neurodegeneration and cognitive impairment. Therefore, the curren...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Ryusuke Takechi, Virginie Lam, Emily Brook, Corey Giles, Nicholas Fimognari, Armin Mooranian, Hani Al-Salami, Stephanie H. Coulson, Michael Nesbit, John C. L. Mamo
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2017-12-01
Rangatū:Frontiers in Aging Neuroscience
Ngā marau:
Urunga tuihono:http://journal.frontiersin.org/article/10.3389/fnagi.2017.00399/full
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