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Differential Activation of TRPM8 by the Stereoisomers of Menthol

The stereoisomers of menthol elicit cooling sensation to various levels. Though the high-resolution three-dimensional structures of the menthol receptor, the transient receptor potential melastatin 8 (TRPM8) ion channels, have been revolved in different states, the menthol-bound state structure is n...

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Autores principales: Xiaoying Chen, Lizhen Xu, Heng Zhang, Han Wen, Fan Yang
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2022-06-01
Colección:Frontiers in Pharmacology
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Acceso en línea:https://www.frontiersin.org/articles/10.3389/fphar.2022.898670/full
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