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The contribution of oral infectious diseases in lacunar stroke based on meta-analysis and Mendelian randomization study

Abstract To investigate the causal relationship between oral infectious diseases and lacunar stroke (LS) and to identify the role of interleukin-1α (IL-1α), interleukin-6 (IL-6), tumor necrosis factor (TNF), and C-reaction protein (CRP) as potential mediators. The meta-analysis incorporating cross-s...

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Principais autores: Qifan Zheng, Tong Xu, Shiyin Luo, Jiahui Zhao, Yue Ying, Nan Liu, Aijia Jiang, Yaping Pan, Dongmei Zhang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2025-05-01
Serier:Scientific Reports
Fag:
Oral infectious diseases
Periodontitis
Lacunar stroke
Mendelian randomization analysis
Meta-analysis
Online adgang:https://doi.org/10.1038/s41598-025-99742-x
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