mRNAs and lncRNAs intrinsically form secondary structures with short end-to-end distances

It was previously suggested that formation of RNA secondary structure tends to bring the 5′ and 3′ ends of RNA into close proximity. Here the authors use experimental and computational approaches to show that mRNAs and lncRNAs have an intrinsic propensity to fold into structures in which the 5′ end...

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מידע ביבליוגרפי

Principais autores:	Wan-Jung C. Lai, Mohammad Kayedkhordeh, Erica V. Cornell, Elie Farah, Stanislav Bellaousov, Robert Rietmeijer, Enea Salsi, David H. Mathews, Dmitri N. Ermolenko
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Nature Portfolio 2018-10-01
סדרה:	Nature Communications
גישה מקוונת:	https://doi.org/10.1038/s41467-018-06792-z
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