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Dihydromyricetin ameliorates hepatic steatosis and insulin resistance via AMPK/PGC-1α and PPARα-mediated autophagy pathway

Abstract Background Dihydromyricetin (DHM), a flavonoid compound of natural origin, has been identified in high concentrations in ampelopsis grossedentata and has a broad spectrum of biological and pharmacological functions, particularly in regulating glucose and lipid metabolism. The objective of t...

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Main Authors: Yan Yang, Wen Qiu, Jiyuan Xiao, Jie Sun, Xuan Ren, Luxia Jiang
Format: Artigo
Language:Inglês
Published: BMC 2024-03-01
Series:Journal of Translational Medicine
Subjects:
Dihydromyricetin
Liver steatosis
Insulin resistance
Autophagy
Online Access:https://doi.org/10.1186/s12967-024-05060-7
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