Fractal analysis of extracellular matrix for observer-independent quantification of intestinal fibrosis in Crohn’s disease

Abstract Prevention of intestinal fibrosis remains an unresolved problem in the treatment of Crohn’s disease (CD), as specific antifibrotic therapies are not yet available. Appropriate analysis of fibrosis severity is essential for assessing the therapeutic efficacy of potential antifibrotic drugs....

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Detalhes bibliográficos

Principais autores:	Marie-Christin Weber, Konstantin Schmidt, Annalisa Buck, Atsuko Kasajima, Simon Becker, Chunqiao Li, Stefan Reischl, Dirk Wilhelm, Katja Steiger, Helmut Friess, Philipp-Alexander Neumann
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2024-02-01
coleção:	Scientific Reports
Assuntos:	Crohn’s disease Intestinal fibrosis Histology Fractal dimension analysis
Acesso em linha:	https://doi.org/10.1038/s41598-024-54545-4
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