Replication competent HIV-guided CRISPR screen identifies antiviral factors including targets of the accessory protein Nef

Abstract Innate antiviral factors are essential for effective defense against viral pathogens. However, the identity of major restriction mechanisms remains elusive. Current approaches to discover antiviral factors usually focus on the initial steps of viral replication and are limited to a single r...

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Xehetasun bibliografikoak

Egile Nagusiak:	Caterina Prelli Bozzo, Alexandre Laliberté, Aurora De Luna, Chiara Pastorio, Kerstin Regensburger, Stefan Krebs, Alexander Graf, Helmut Blum, Meta Volcic, Konstantin M. J. Sparrer, Frank Kirchhoff
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Nature Portfolio 2024-05-01
Saila:	Nature Communications
Sarrera elektronikoa:	https://doi.org/10.1038/s41467-024-48228-x
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