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Cyclophilin A induces macrophage apoptosis and enhances atherosclerotic lesions in high‐fat diet‐fed hyperglycemic rabbits

Abstract Macrophage apoptosis is a key contributor to the progression of atherosclerosis. Cyclophilin A, a monocyte secretory protein associated with the initiation of atherosclerosis has an inherent nuclease activity. This study reports the mechanism by which cyclophilin A causes apoptosis of macro...

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Bibliografiset tiedot
Päätekijät: Vinitha Anandan, Santhosh Kumar Thankayyan Retnabai, Abdul Jaleel, Thushara Thulaseedharan, Ajit Mullasari, M. Radhakrishna Pillai, Cheranellore Chandrasekharan Kartha, Surya Ramachandran
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Wiley 2021-05-01
Sarja:FASEB BioAdvances
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Linkit:https://doi.org/10.1096/fba.2020-00135
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