Human papillomavirus-related oropharyngeal squamous cell carcinoma exhibits enhanced radiosensitivity despite limited activation of cytosolic DNA sensing pathways and innate immune responses

Pharyngeal squamous cell carcinoma (PSCC) is a significant health concern, with human papillomavirus 16 (HPV16) playing a key role in the etiology of oropharyngeal squamous cell carcinoma (OPSCC). HPV16-related OPSCC exhibits enhanced radiosensitivity compared to HPV16-unrelated PSCC, yet the underl...

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Hlavní autoři:	Levpuscek Kristina, Jesenko Tanja, Komel Tilen, Brezar Simona Kranjc, Sersa Gregor, Cemazar Maja, Strojan Primoz
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Sciendo 2025-12-01
Edice:	Radiology and Oncology
Témata:	cytosolic dna sensing pathways innate immune response human papillomavirus type 16 pharyngeal squamous cell carcinoma radiation responseintroduction
On-line přístup:	https://doi.org/10.2478/raon-2025-0057
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