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Advances in biomarkers of resistance to KRAS mutation-targeted inhibitors

Abstract KRAS mutations represent the most common driver genetic alterations in multiple malignant tumors, particularly exerting well-defined oncogenic driver roles in non-small cell lung cancer, colorectal cancer, and pancreatic ductal adenocarcinoma. The recent success of KRAS G12C mutation-specif...

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Detalles Bibliográficos
Principais autores: Lihao Wang, Dandan Wei, Shanshan Li, Shiqing Jiang
Formato: Artigo
Idioma:Inglês
Publicado: Springer 2025-10-01
Series:Discover Oncology
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Acceso en liña:https://doi.org/10.1007/s12672-025-03569-x
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