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IFITM2 Presents Antiviral Response through Enhancing Type I IFN Signaling Pathway

Interferon (IFN) helps cells fight viral infections by further inducing the expression of many downstream IFN-stimulated genes (ISGs). Human interferon-inducible transmembrane proteins (IFITM) are one of these ISGs. The antiviral function of human IFITM1, IFITM2, and IFITM3 are well known. In this s...

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Principais autores: Lei Chen, Xiangrong Li, Yingying Deng, Yingjie Bi, Zhenfang Yan, Yanmei Yang, Xiangbo Zhang, Huixia Li, Jingying Xie, Ruofei Feng
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-03-01
Serier:Viruses
Fag:
IFITM2 protein
type I interferon
antiviral effect
MDA5
innate immune response
Online adgang:https://www.mdpi.com/1999-4915/15/4/866
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