Bakuchiol kills Staphylococcus aureus persisters and potentiates colistin activity against Acinetobacter baumannii persisters

Infections associated with bacterial persisters are challenging to cure because they can evade antibiotics and regrow, often resulting in relapse. Current antibiotics are not optimized to target persisters, highlighting the urgent need for new therapeutics. Here, we report that bakuchiol, a plant-de...

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Autori principali:	Kayeong Suh, Yeju Lee, Seongeun Baek, Jin Kim, Jinbeom Seo, Yung-Hun Yang, Jae-Seok Kim, Wonsik Lee, Eun Kyoung Seo, Wooseong Kim
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2025-05-01
Serie:	Frontiers in Pharmacology
Soggetti:	persisters antibiotic resistance natural products MRSA Acinetobacterbaumannii
Accesso online:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1592183/full
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