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A circuitous route for in vitro multi-enzyme cascade production of cytidine triphosphate to overcome the thermodynamic bottleneck

Abstract Cytidine triphosphate (CTP), as a substance involved in the metabolism of phospholipids, proteins and nucleic acids, has precise drug effects and is a direct precursor for the synthesis of drugs such as citicoline. In this study, we established an in vitro six-enzyme cascade system to gener...

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Bibliografiske detaljer
Principais autores: Zonglin Li, Yahui Zhong, Zhoulei Qing, Zhimin Li
Format: Artigo
Sprog:Inglês
Udgivet: SpringerOpen 2024-01-01
Serier:Bioresources and Bioprocessing
Fag:
Online adgang:https://doi.org/10.1186/s40643-023-00724-6
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