Varenicline improves cognitive impairment in a mouse model of mPFC ischemia: The possible roles of inflammation, apoptosis, and synaptic factors

Ischemia in the medial prefrontal cortex (mPFC) causes cognitive impairment in stroke cases. This study aimed to examine the effects of varenicline as α7 and α4β2 nicotine acetylcholine receptors (nAChRs) agonist, on cognitive impairment, inflammation, apoptosis, and synaptic dysfunction in mPFC isc...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Fatemehsadat Seyedaghamiri, Leila Hosseini, Sareh Kazmi, Javad Mahmoudi, Dariush Shanehbandi, Abbas Ebrahimi-Kalan, Reza Rahbarghazi, Saeed Sadigh-Eteghad, Mehdi Farhoudi
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2022-04-01
Schriftenreihe:	Brain Research Bulletin
Schlagworte:	Brain ischemia Varenicline Medial prefrontal cortex Memory Anxiety
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S0361923022000144
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