Single-cell RNA sequencing reveals immunosuppressive myeloid cell diversity during malignant progression in a murine model of glioma

Summary: Recent studies have shown the importance of the dynamic tumor microenvironment (TME) in high-grade gliomas (HGGs). In particular, myeloid cells are known to mediate immunosuppression in glioma; however, it is still unclear if myeloid cells play a role in low-grade glioma (LGG) malignant pro...

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Prif Awduron:	Sakthi Rajendran, Yang Hu, Alessandro Canella, Clayton Peterson, Amy Gross, Maren Cam, Matthew Nazzaro, Abigail Haffey, Akdes Serin-Harmanci, Rosario Distefano, Giovanni Nigita, Wesley Wang, Daniel Kreatsoulas, Zihai Li, Jesse A. Sepeda, Andrew Sas, Mark E. Hester, Katherine E. Miller, Olivier Elemento, Ryan D. Roberts, Eric C. Holland, Ganesh Rao, Elaine R. Mardis, Prajwal Rajappa
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2023-03-01
Cyfres:	Cell Reports
Pynciau:	CP: Neuroscience CP: Cancer
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S2211124723002085
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