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Potential Metabolic Drug–Drug Interaction of Citrus aurantium L. (Rutaceae) Evaluating by Its Effect on 3 CYP450

Aim:Fructus aurantii (FA) is widely used in clinic as an expectorant and digestant herb in traditional Chinese medicine and proven to have a variety of pharmacological functions. FA is close to grapefruit either by botanical taxonomy or by their same components (flavonoids, etc.) and grapefruit has...

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Uloženo v:
Hlavní autoři: Lu Zhou, Man Cui, Linlin Zhao, Dongsheng Wang, Tao Tang, Wenbo Wang, Sheng Wang, Huiyong Huang, Xinjian Qiu
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018-08-01
Edice:Frontiers in Pharmacology
Témata:
Fructus aurantii
CYP1A2
CYP3A4
CYP2E1
drug–drug interaction
On-line přístup:https://www.frontiersin.org/article/10.3389/fphar.2018.00895/full
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