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Down‐regulation of the Sp1 transcription factor by an increase of microRNA-4497 in human placenta is associated with early recurrent miscarriage

Abstract Background The pathophysiological mechanism of recurrent miscarriage (RM) is unclear. The goals of this study were to determine the role of microRNA-4497 overexpression in placental villus tissues in early RM; To identify the potential target mRNAs of miRNA-4497; And to investigate the micr...

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Principais autores: Huaiyun Tang, Linqing Pan, Yun Xiong, Leilei Wang, Yugui Cui, Jiayin Liu, Lisha Tang
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2021-02-01
coleção:Reproductive Biology and Endocrinology
Assuntos:
Recurrent miscarriage
MicroRNA-4497
Sp1
Placenta
Chorionic Trophoblast
Acesso em linha:https://doi.org/10.1186/s12958-021-00701-8
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