Genetic anticipation in Swedish Lynch syndrome families.

Among hereditary colorectal cancer predisposing syndromes, Lynch syndrome (LS) caused by mutations in DNA mismatch repair genes MLH1, MSH2, MSH6 or PMS2 is the most common. Patients with LS have an increased risk of early onset colon and endometrial cancer, but also other tumors that generally have...

Fuld beskrivelse

Bibliografiske detaljer

Principais autores:	Jenny von Salomé, Philip S Boonstra, Masoud Karimi, Gustav Silander, Marie Stenmark-Askmalm, Samuel Gebre-Medhin, Christos Aravidis, Mef Nilbert, Annika Lindblom, Kristina Lagerstedt-Robinson
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science (PLoS) 2017-10-01
Serier:	PLoS Genetics
Online adgang:	https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1007012&type=printable
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!