Insights into Transient Dimerisation of Carnitine/Acylcarnitine Carrier (SLC25A20) from Sarkosyl/PAGE, Cross-Linking Reagents, and Comparative Modelling Analysis

The carnitine/acylcarnitine carrier (CAC) is a crucial protein for cellular energy metabolism, facilitating the exchange of acylcarnitines and free carnitine across the mitochondrial membrane, thereby enabling fatty acid β-oxidation and oxidative phosphorylation (OXPHOS). Although CAC has not been c...

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Bibliographic Details

Main Authors:	Nicola Giangregorio, Annamaria Tonazzi, Ciro Leonardo Pierri, Cesare Indiveri
Format:	Artigo
Language:	Inglês
Published:	MDPI AG 2024-09-01
Series:	Biomolecules
Subjects:	mitochondrial carriers oligomeric structure homodimer carnitine/acylcarnitine carrier (CAC) SLC25A20 purification–reconstitution–transport
Online Access:	https://www.mdpi.com/2218-273X/14/9/1158
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