Macrophage-infectivity potentiator of Trypanosoma cruzi (TcMIP) is a new pro-type 1 immuno-stimulating protein for neonatal human cells and vaccines in mice

This work identifies the protein “macrophage infectivity potentiator” of Trypanosoma cruzi trypomastigotes, as supporting a new property, namely a pro-type 1 immunostimulatory activity on neonatal cells. In its recombinant form (rTcMIP), this protein triggers the secretion of the chemokines CCL2 and...

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Hlavní autoři:	Magdalena Radwanska, Frédéric de Lemos Esteves, Loes Linsen, Nicolas Coltel, Sabrina Cencig, Joelle Widart, Anne-Cécile Massart, Séverine Colson, Alexandre Di Paolo, Pauline Percier, Sarra Ait Djebbara, François Guillonneau, Véronique Flamand, Edwin De Pauw, Jean-Marie Frère, Yves Carlier, Carine Truyens
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-03-01
Edice:	Frontiers in Immunology
Témata:	neonatal immunity adjuvant cord blood type 1 immune response gamma-interferon macrophage infectivity potentiator
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1138526/full
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