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Constitutive, Muscle-Specific <i>Orai1</i> Knockout Results in the Incomplete Assembly of Ca<sup>2+</sup> Entry Units and a Reduction in the Age-Dependent Formation of Tubular Aggregates

Store-operated Ca<sup>2+</sup> entry (SOCE) is a ubiquitous cellular mechanism that cells use to activate extracellular Ca<sup>2+</sup> entry when intracellular Ca<sup>2+</sup> stores are depleted. In skeletal muscle, SOCE occurs within Ca<sup>2+</sup> entry units (CEUs), intracellular junctions bet...

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Автори: Alessia Di Fonso, Matteo Serano, Miao He, Jennifer Leigh, Giorgia Rastelli, Robert T. Dirksen, Feliciano Protasi, Laura Pietrangelo
Формат: Artigo
Мова:Inglês
Опубліковано: MDPI AG 2024-07-01
Серія:Biomedicines
Предмети:
sarcoplasmic reticulum
skeletal muscle
store-operated Ca<sup>2+</sup> entry
tubular aggregate myopathy
Онлайн доступ:https://www.mdpi.com/2227-9059/12/8/1651
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