Oxidative stress promotes ventilator-induced lung injury through activating NLRP3 inflammasome and TRPM2 channel

Ventilator has been widely used for life support, but ventilator-induced lung injury (VILI) is still a major problem. Oxidative stress has been considered as a key contributor for VILI, but the specific mechanism remains unclear. The expression of NLRP3 inflammasome in cells and inflammatory factors...

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Autori principali:	Xiaona An, Xiaotong Sun, Xiaomei Yang, Dejie Liu, Yonghao Hou, Hongli Chen, Jianbo Wu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis Group 2019-12-01
Serie:	Artificial Cells, Nanomedicine, and Biotechnology
Soggetti:	Ventilator-induced lung injury TRPM2 channel NLRP3 inflammasome IL-1β IL-18
Accesso online:	https://www.tandfonline.com/doi/10.1080/21691401.2019.1652631
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