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Dissecting Murine Muscle Stem Cell Aging through Regeneration Using Integrative Genomic Analysis

Summary: During aging, there is a progressive loss of volume and function in skeletal muscle that impacts mobility and quality of life. The repair of skeletal muscle is regulated by tissue-resident stem cells called satellite cells (or muscle stem cells [MuSCs]), but in aging, MuSCs decrease in numb...

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I tiakina i:
Ngā kaituhi matua: Anna Shcherbina, Jacqueline Larouche, Paula Fraczek, Benjamin A. Yang, Lemuel A. Brown, James F. Markworth, Carolina H. Chung, Mehwish Khaliq, Kanishka de Silva, Jeongmoon J. Choi, Mohammad Fallahi-Sichani, Sriram Chandrasekaran, Young C. Jang, Susan V. Brooks, Carlos A. Aguilar
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2020-07-01
Rangatū:Cell Reports
Ngā marau:
regeneration
heterochromatin
expression
vitamin A
1-carbon metabolism
MyoD
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2211124720309451
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