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Cdc42 Promotes Axonogenesis of Primary Hippocampal Neurons by Inhibiting Glycogen Synthase Kinase-3β

Background: Progressive axon degeneration is a common pathological feature of neurodegenerative diseases. Cdc42 is a member of the Rho GTPase family that participates in axonogenesis. GSK-3β is a serine/threonine kinase highly implicated in neuronal development and neurodegeneration. This study aime...

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Principais autores: Yu-Ting Li, Fang-Zheng Chen, Wei Chen, Hui-Ming Zhu, Yu Chen, Zhen-Lin Li, Fang Yan, Zhong-Ying Liu, Wei-Ren Dong, Lin Zhang, Hai-Hong Wang
Format: Artigo
Sprog:Inglês
Udgivet: IMR Press 2022-07-01
Serier:Journal of Integrative Neuroscience
Fag:
cdc42
axonogenesis
hippocampal neurons
gsk-3β
crmp-2
Online adgang:https://www.imrpress.com/journal/JIN/21/5/10.31083/j.jin2105133
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