APR-246 increases tumor antigenicity independent of p53

Michels, Venkatesh et al demonstrate that APR-246, a small molecule Michael acceptor, enhances tumor immunogenicity. Combination of APR-246 with immune modulation enhances antitumor responses. APR-246, initially described as a P53 stabilizer, induces immunogenicity irrespective of the tumor’s p53 st...

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Bibliografiske detaljer

Principais autores:	Judith Michels, Divya Venkatesh, Cailian Liu, Sadna Budhu, Hong Zhong, Mariam M George, Daniel Thach, Zhong-Ke Yao, Ouathek Ouerfelli, Hengrui Liu, Brent R Stockwell, Luis Felipe Campesato, Dmitriy Zamarin, Roberta Zappasodi, Jedd D Wolchok, Taha Merghoub
Format:	Artigo
Sprog:	Inglês
Udgivet:	Life Science Alliance LLC 2024-01-01
Serier:	Life Science Alliance
Online adgang:	https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202301999
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