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Neuronal Apoptosis Induced by β-Amyloid Is Mediated by Caspase-8

The Alzheimer disease-associated β-amyloid peptide has been shown to induce apoptotic neuronal death. In the present study, we test the hypothesis that the apoptotic pathway activated by β-amyloid is similar to the pathway activated by the Fas/TNFR family of death receptors, which requires caspase-8...

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Principais autores: Kathryn J. Ivins, Phillip L. Thornton, Troy T. Rohn, Carl W. Cotman
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 1999-10-01
coleção:Neurobiology of Disease
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0969996199902681
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