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Mutations in TP53 are exclusively associated with del(17p) in multiple myeloma

Deletion of the 17p13 chromosomal region [del(17p)] is associated with a poor outcome in multiple myeloma. Most of the studies have targeted the TP53 gene for deletion analyses, although no study showed that this gene is the deletion target. In order to address this issue, we sequenced the TP53 gene...

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Autori principali: Laurence Lodé, Marion Eveillard, Valérie Trichet, Thierry Soussi, Soraya Wuillème, Steven Richebourg, Florence Magrangeas, Norbert Ifrah, Loïc Campion, Catherine Traullé, François Guilhot, Denis Caillot, Gérald Marit, Claire Mathiot, Thierry Facon, Michel Attal, Jean-Luc Harousseau, Philippe Moreau, Stéphane Minvielle, Hervé Avet-Loiseau
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2010-11-01
Serie:Haematologica
Accesso online:https://haematologica.org/article/view/5797
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