Multi-parametric photoacoustic elastomicroscopy: quantitative elasticity mapping and microstructural analysis for early-stage hepatic fibrosis detection

Early detection of hepatic fibrosis remains a critical unmet need due to the limited sensitivity of conventional elastography in capturing microstructural and biomechanical changes. In this study, we developed photoacoustic elastomicroscopy (PAEM), a multi-parametric imaging platform that synergizes...

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Autores principales: Weiran Pang, Qi Zhou, Yang Qiu, Haofan Huang, Jiali Chen, Tianting Zhong, Yingying Zhou, Liming Nie, Puxiang Lai
Formato: Artigo
Lenguaje:Inglês
Publicado: IOP Publishing 2025-01-01
Colección:JPhys Photonics
Materias:
photoacoustic elastomicroscopy (PAEM)
liver fibrosis
tissue stiffness
time of flight (ToF)
elastic sensing and measurement
tumor margins
Acceso en línea:https://doi.org/10.1088/2515-7647/ae0541
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