Analysis of mRNA Decay Intermediates in Bacillus subtilis 3′ Exoribonuclease and RNA Helicase Mutant Strains

ABSTRACT The Bacillus subtilis genome encodes four 3′ exoribonucleases: polynucleotide phosphorylase (PNPase), RNase R, RNase PH, and YhaM. Previous work showed that PNPase, encoded by the pnpA gene, is the major 3′ exonuclease involved in mRNA turnover; in a pnpA deletion strain, numerous mRNA deca...

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Hlavní autoři:	Shivani Chhabra, Zachary F. Mandell, Bo Liu, Paul Babitzke, David H. Bechhofer
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2022-04-01
Edice:	mBio
Témata:	Bacillus subtilis mRNA decay 3′ exoribonucleases RNA helicase PNPase Term-seq
On-line přístup:	https://journals.asm.org/doi/10.1128/mbio.00400-22
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