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METTL14-Mediated m6A Modification of TUG1 Represses Ferroptosis in Alzheimer's Disease via Inhibiting GDF15 Ubiquitination

Background: Alzheimer’s disease (AD) is a neurodegenerative disease that remains a serious global health issue. Ferroptosis has been recognized as a vital driver of pathological progression of AD. However, the detailed regulatory mechanisms of ferroptosis during AD progression remain unclear. This s...

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Principais autores: Xunhu Gu, Yuanqing Song, Xu Liu, Zhijuan Cheng, Jun Min, Yangbo Zhang
Format: Artigo
Sprog:Inglês
Udgivet: IMR Press 2024-08-01
Serier:Frontiers in Bioscience-Landmark
Fag:
alzheimer's disease
ferroptosis
mettl14
m6a modification
gdf15
Online adgang:https://www.imrpress.com/journal/FBL/29/8/10.31083/j.fbl2908298
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