Effects of Anticancer Agent P-bi-TAT on Gene Expression Link the Integrin Thyroid Hormone Receptor to Expression of Stemness and Energy Metabolism Genes in Cancer Cells

Chemically modified forms of tetraiodothyroacetic acid (tetrac), an L-thyroxine derivative, have been shown to exert their anticancer activity at plasma membrane integrin αvβ3 of tumor cells. Via a specific hormone receptor on the integrin, tetrac-based therapeutic agents modulate expression of gene...

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Главные авторы:	Gennadi V. Glinsky, Kavitha Godugu, Thangirala Sudha, Mehdi Rajabi, Sridar V. Chittur, Aleck A. Hercbergs, Shaker A. Mousa, Paul J. Davis
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2022-04-01
Серии:	Metabolites
Предметы:	ATP synthase cancer cells mitochondria glioblastoma integrin αvβ3 NADH dehydrogenase
Online-ссылка:	https://www.mdpi.com/2218-1989/12/4/325
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