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Marine natural product lepadin A as a novel inducer of immunogenic cell death via CD91-dependent pathway

Abstract Immunogenic Cell Death (ICD) represents a mechanism of enhancing T cell-driven response against tumor cells. The process is enabled by release of damage-associated molecular patterns (DAMPs) and cytokines by dying cells. Based on molecular studies and clinical marker assessment, ICD can be...

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Principais autores: Dalila Carbone, Carmela Gallo, Genoveffa Nuzzo, Giusi Barra, Mario Dell’Isola, Mario Affuso, Olimpia Follero, Federica Albiani, Clementina Sansone, Emiliano Manzo, Giuliana d’Ippolito, Angelo Fontana
Format: Artigo
Sprog:Inglês
Udgivet: SpringerOpen 2023-10-01
Serier:Natural Products and Bioprospecting
Fag:
Immunogenic cell death
Natural products
Anticancer
Immunotherapy
Drug discovery
Online adgang:https://doi.org/10.1007/s13659-023-00401-3
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